Melanie Smith

Hertz Fellow: Melanie Smith
School

University of California, San Francisco

Area of Study

Quantitative Biology and Applied Physics

Fellowship Years

2010 - 2014

Protein structure and interactions have been the focus of Melanie’s PhD/MD research. Her work on the distinction between properly made and improperly made proteins and how the cell disposes of those that are improperly made has important implications for many disease processes including the survival of cancer cells and immune system activation. She is currently finishing the MD portion of the program at UC San Francisco. After completing the MD, she plans to bring her research and work as an MD together by exploring mechanisms of autoimmunity with a focus on protein-protein interactions.

Thesis:

2014 - The Recognition, Regulation and Roles of Misfolded Proteins in the Cell